The hemodynamics of the Replicator delivers a realistic cardiac output similar to physiological flows, supporting true device performance for device development and training.
LIMITLESS NEUROVASCULAR CONFIGURATIONS
Configure a head or box with a variety of neurovascular disease states that are easily replaceable.
LIFE-LIKE RESULTS WITH REPEATABILITY
Easily and repeatedly simulate procedures at product demonstrations, training sessions, and more.
Extraordinarily Realistic Experience When Simulating Neurovascular Procedures
PATIENT-SPECIFIC CONFIGURATIONS – strokes, aneurysms, AVMs, Circle of Willis, and more
MULTIPLE ACCESS – femoral artery access with radial access extension capability
“We rehearsed the procedure on a patient-specific Replicator system model (Vascular Simulations, Stony Brook, New York, USA) of the patient’s cervical and cerebral vasculature. The rehearsal confirmed our concerns about the difficulty of accessing the vertebral artery distal to the aneurysm; and ‘around the dome’ technique was required to gain microwire access to the distal parent artery.”
Edward AM Duckworth et al.
The First North American use of the Pipeline Flex Flow Diverter.
Journal of Neurointerventional Surgery. 2016.
LIFE-LIKE SIMULATION FOR TRUE DEVICE PERFORMANCE
The Replicator duplicates the cardiac cycle with a functional left atrium and ventricle with mechanical mitral and aortic valves. The “blood flow” then passes through a silicone aorta with a compliance that recreates the clinical Windkessel effect. This results in pressure waveforms in the aorta of the replicator that are indistinguishable from the waveforms of a human aorta.
The great vessels arising from the aortic arch and the cerebrovasculature can be prototyped from imaging studies of actual patients and their entire vascular anatomy and pathology can be recreated with silicone. Virtually, any intracranial aneurysm can be recreated and placed within Replicator’s truly clinically relevant environment.
A proprietary clear blood analog with a viscosity matching that of human blood duplicates the friction coefficients of endovascular devices, wires, and catheters as they traverse the vascular system. The blood analog fluid is automatically warmed up to body temperature (98.6 °F) by the Replicator. In addition, the cerebrovasculature is housed in a polyurethane “head” filled with a gel that mimics the compliance of the brain parenchyma. As a result, the passage of wires and catheters into the cerebrovasculature mimics the straightening of vessels as visualized clinically.
The Replicator comes with a Windows laptop with a pre-installed software application that operates the Replicator via Bluetooth connectivity. Software functions include filling, running, and draining the Replicator, as well as controls to change the heart rate and mean blood flow rates to the Head and Body.
The whole system can be placed in any fluoroscopic environment and imaging can be performed in any machine including biplane angiography systems. Standard fluoroscopy, roadmap imaging, digital subtraction angiography and rotational angiography can be performed with any contrast agent and acquisition sequences identical to real clinical cases can be obtained.
THE ULTIMATE ACADEMIC AND CLINICAL SOLUTION
OUR SIMULATION GOES FAR BEYOND
Academic researchers, clinical coordinators, and more professionals are able to experience extraordinarily realistic simulation with Replicator.
Hemodynamic outputs are similar to physiological flows, all while being easily repeatable and compatible with most devices and tools.
The system can be used in the angiographic environment in combination with any endovascular access product or device utilized to replicate an actual clinical case.
This allows neurovascular device professionals within training, research, development, marketing, and more, to reach goals far beyond limits with life-like simulation.